PEPTIDE

TB500

TB-500 is a synthetic peptide corresponding to the active domain of human Thymosin Beta-4 (Tβ4). It regulates actin cytoskeletal dynamics to promote cell migration, angiogenesis, multi-tissue repair, and inflammation-pathway research observations, making it a core research tool for wound healing and regenerative biology studies.

TB-500 is a metabolically stable synthetic peptide matching the conserved active domain of human Thymosin Beta-4 (Tβ4), one of the most abundant intracellular regulatory peptides in mammalian tissue. Optimized for regenerative research, it retains the core biological activity of full-length Tβ4:

Core Mechanism & Key Properties

High-affinity binding to monomeric G-actin (globular actin), sequestering it to dynamically regulate cytoskeletal polymerization: this enables directed cell migration, cellular shape change, and coordinated tissue remodeling at injury sites
Stimulates VEGF-mediated angiogenesis to form new microvessels, delivering nutrients and oxygen to regenerating tissue
Modulates pro-inflammatory cytokine signaling to reduce excessive, damaging inflammation at injury sites
Supports stem cell differentiation and cell proliferation to accelerate functional tissue regeneration

Primary Research Applications

Preclinical studies of soft tissue repair (muscle, tendon, ligament, and connective tissue)
Cutaneous wound healing and post-surgical recovery models
Cardiovascular and dermal angiogenesis research
Anti-inflammatory and chronic tissue remodeling studies

Manufactured to ≥99% purity, sterile-filtered, and lyophilized for long-term storage stability.

For laboratory research use only; not intended for human or veterinary administration.

Research use only: This material is supplied for laboratory research and documentation workflows only. It is not intended for human consumption, diagnostic use, therapeutic use, veterinary use or clinical application.

Hytan procurement and documentation support

For TB500, Hytan Peptides can support research-use sourcing review with available batch COA, vial labeling, product identity notes, storage documentation and wholesale quantity discussion. Product-specific CAS, sequence, molecular weight or method details should be confirmed against the current batch document before procurement decisions.

COA review: request batch-specific purity and identity references where available.
Wholesale planning: confirm vial strength, quantity, lead time, packing and destination requirements.
Compliance: research-use wording should remain clear in quote, invoice and receiving records.

Manufacturing Capability

Controlled production for consistent research peptide supply

Hytan Peptides supports wholesale research peptide orders with organized production workflow, clean handling, standardized filling, labeling and batch-level documentation. From material preparation to final review, each step is managed to support consistent appearance, traceable COA records and dependable supply coordination.

This production overview helps laboratories, distributors and qualified research buyers understand how Hytan Peptides approaches quality-focused peptide manufacturing, packaging and order readiness.