PEPTIDE

SS-31

SS-31 (Elamipretide) is a cell-permeable aromatic-cationic tetrapeptide that selectively targets and accumulates in the inner mitochondrial membrane. It binds cardiolipin to stabilize mitochondrial cristae structure, enhance ATP production, reduce reactive oxygen species (ROS), and protect mitochondria from oxidative damage, making it a core tool for mitochondrial function and aging research.

SS-31 (also known as Elamipretide, Bendavia, MTP-131) is a synthetic cell-permeable aromatic-cationic tetrapeptide, the most extensively studied mitochondria-targeted protective peptide for metabolic and degenerative disease research:

Core Mechanism & Defining Properties

Selectively accumulates >1,000-fold in the inner mitochondrial membrane via electrostatic attraction to negatively charged cardiolipin, a phospholipid critical for mitochondrial cristae structure and electron transport chain (ETC) function
Stabilizes mitochondrial cristae architecture, enhances ETC efficiency, and boosts cellular ATP production
Scavenges reactive oxygen species (ROS), inhibits cardiolipin peroxidation, and prevents cytochrome c release to reduce mitochondrial oxidative damage and apoptotic signaling
Penetrates cell membranes independently of mitochondrial membrane potential, enabling it to target dysfunctional, depolarized mitochondria that conventional cytoplasmic antioxidants cannot reach
Exerts no adverse effects on healthy, normally functioning mitochondria

Primary Research Applications

Mitochondrial bioenergetics and function regulation research
Ischemia-reperfusion injury models (cardiac, renal, and neurological tissue)
Aging biology and age-related mitochondrial functional decline studies
Preclinical models of neurodegeneration, heart failure, and chronic kidney disease
Oxidative stress and mitochondrial dysfunction research research

Manufactured to ≥99% purity, sterile-filtered, and lyophilized for long-term storage stability.

For laboratory research use only; not intended for human or veterinary administration.

Research use only: This material is supplied for laboratory research and documentation workflows only. It is not intended for human consumption, diagnostic use, therapeutic use, veterinary use or clinical application.

Hytan procurement and documentation support

For SS-31, Hytan Peptides can support research-use sourcing review with available batch COA, vial labeling, product identity notes, storage documentation and wholesale quantity discussion. Product-specific CAS, sequence, molecular weight or method details should be confirmed against the current batch document before procurement decisions.

COA review: request batch-specific purity and identity references where available.
Wholesale planning: confirm vial strength, quantity, lead time, packing and destination requirements.
Compliance: research-use wording should remain clear in quote, invoice and receiving records.

Manufacturing Capability

Controlled production for consistent research peptide supply

Hytan Peptides supports wholesale research peptide orders with organized production workflow, clean handling, standardized filling, labeling and batch-level documentation. From material preparation to final review, each step is managed to support consistent appearance, traceable COA records and dependable supply coordination.

This production overview helps laboratories, distributors and qualified research buyers understand how Hytan Peptides approaches quality-focused peptide manufacturing, packaging and order readiness.