Selank
Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin, developed by the Russian Academy of Sciences. It delivers anxiolytic (anti-anxiety) and nootropic (cognitive-enhancing) effects without sedation or dependence risk, modulating GABAergic signaling, stabilizing enkephalins, and upregulating BDNF to support mood stability, memory, and stress resilience.
Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin, developed and extensively studied by the Institute of Molecular Genetics, Russian Academy of Sciences, for neuropsychiatric and cognitive research:
Core Mechanism & Key Properties
- Modulates GABAergic signaling to reduce anxiety without sedation, cognitive impairment, or dependence risk (a critical distinction from benzodiazepine anxiolytics)
- Stabilizes endogenous enkephalins to regulate mood and stress response, and upregulates brain-derived neurotrophic factor (BDNF) to support neuroplasticity, memory, and learning
- Exerts mild immunomodulatory effects inherited from its parent peptide tuftsin
- Has a favorable safety profile with no reported abuse potential or cognitive side effects in preclinical and early clinical research
Primary Research Applications
- Anxiety and stress resilience research
- Cognitive enhancement, memory, and neuroplasticity studies
- Mood regulation and stress-related neuropsychiatric disorder models
- Neuroimmune modulation and neuroprotective research
Manufactured to ≥98% purity, sterile-filtered, and lyophilized for long-term stability.
For laboratory research use only; not intended for human or veterinary administration.
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