PEPTIDE

Epithalon

Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from pineal gland epithalamin. It is a foundational longevity research peptide that activates telomerase reverse transcriptase (TERT) to maintain telomere length, delay cellular senescence, and support circadian regulation, antioxidant defense, and immune function in aging biology studies.

Epithalon (also referred to as Epitalon) is a synthetic 4-amino acid tetrapeptide (sequence: Ala-Glu-Asp-Gly), corresponding to the active domain of the pineal gland-derived polypeptide epithalamin, developed and extensively studied for gerontology and longevity research:

Core Mechanism & Key Properties

Activates telomerase reverse transcriptase (TERT), the catalytic subunit of the telomerase enzyme, to extend and maintain telomere length (the protective nucleotide caps at chromosome ends that shorten with each cell division, driving replicative cellular senescence)
Penetrates cell and nuclear membranes to act as an epigenetic regulator, modifying chromatin structure and modulating expression of age-related regulatory genes
Regulates pineal melatonin synthesis to normalize circadian rhythm homeostasis
Exerts antioxidant, DNA repair-enhancing, and immunomodulatory effects to mitigate age-related cellular damage and functional decline

Primary Research Applications

Longevity and gerontology research (telomere biology, cellular senescence, and age-related degenerative processes)
Circadian rhythm and pineal gland function studies
DNA damage repair and oxidative stress response research
Immunosenescence and age-related immune decline investigations

Manufactured to ≥99% purity, sterile-filtered, and lyophilized for long-term storage stability.

For laboratory research use only; not intended for human or veterinary administration.

Research use only: This material is supplied for laboratory research and documentation workflows only. It is not intended for human consumption, diagnostic use, therapeutic use, veterinary use or clinical application.

Hytan procurement and documentation support

For Epithalon, Hytan Peptides can support research-use sourcing review with available batch COA, vial labeling, product identity notes, storage documentation and wholesale quantity discussion. Product-specific CAS, sequence, molecular weight or method details should be confirmed against the current batch document before procurement decisions.

COA review: request batch-specific purity and identity references where available.
Wholesale planning: confirm vial strength, quantity, lead time, packing and destination requirements.
Compliance: research-use wording should remain clear in quote, invoice and receiving records.

Manufacturing Capability

Controlled production for consistent research peptide supply

Hytan Peptides supports wholesale research peptide orders with organized production workflow, clean handling, standardized filling, labeling and batch-level documentation. From material preparation to final review, each step is managed to support consistent appearance, traceable COA records and dependable supply coordination.

This production overview helps laboratories, distributors and qualified research buyers understand how Hytan Peptides approaches quality-focused peptide manufacturing, packaging and order readiness.