CJC 1295 (with/without DAC)
CJC-1295 is a stabilized synthetic analog of human growth hormone-releasing hormone (GHRH), available in two research formulations:
- CJC-1295 (No DAC / Mod GRF 1-29): Short-acting, produces physiological pulsatile growth hormone (GH) release mimicking natural endogenous secretion
- CJC-1295 (With DAC): Long-acting, using Drug Affinity Complex (DAC) albumin-binding technology to deliver sustained GH elevation for 6–8 days per dose. Both are used to study GH secretion, body composition modulation, muscle anabolism, fat metabolism, and exercise recovery.
CJC-1295 is an enzyme-stabilized synthetic analog of human growth hormone-releasing hormone (GHRH), designed to selectively stimulate growth hormone (GH) secretion from pituitary somatotroph cells. It is manufactured in two distinct, research-optimized formulations:
1. CJC-1295 Without DAC (Mod GRF 1-29)
- A 29-amino acid modified GHRH analog with a ~30-minute circulating half-life
- Produces physiological pulsatile GH release that replicates natural endogenous GH secretion patterns, preserving long-term GH receptor sensitivity
- The gold-standard short-acting GHRH analog for research, widely used in synergistic stacks with GHRP peptides (e.g., Ipamorelin) to amplify GH secretion
- Core research applications: body composition studies (muscle anabolism, fat loss), exercise recovery models, and physiological GH regulation research
2. CJC-1295 With DAC
- Incorporates proprietary Drug Affinity Complex (DAC) technology: a maleimido-lysine linker that covalently binds to serum albumin, extending the peptide’s functional half-life to 6–8 days
- Delivers sustained, steady GH elevation over multiple days from a single dose, eliminating frequent dosing requirements
- Core research applications: long-term GH modulation studies, chronic body composition intervention models, and extended-duration GH secretion research
Both formulations are produced to ≥98% purity, sterile-filtered, and lyophilized for long-term storage stability.
For laboratory research use only; not intended for human or veterinary administration.
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